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Mayo, Charles Horace
 (mā´ō) , 1865—1939, American surgeon, b. Rochester, Minn., M.D. Northwestern Univ., 1888. He specialized in goiter and cataract operations. His brother, William James Mayo, 1861—1939, b. Le Sueur, Minn., M.D. Univ. of Michigan, 1883, was also a surgeon; he specialized in abdominal surgery. From a small clinic opened by their father, William Worrall Mayo, in Rochester, Minn., in 1889, the brothers developed the great Mayo Clinic of international reputation. In 1915 they established the Mayo Foundation for Medical Education and Research as a branch of the graduate school of the Univ. of Minnesota.

See G. W. Nagel, The Mayo Legacy (1966); H. Clapesattle, The Doctors Mayo (2d ed. 1968); C. W. Mayo, The Story of My Family and My Career (1968).